Stimuli Responsive Biomaterials Market, By Type (Temperature-Responsive, pH-Responsive, Light-Responsive, Magnetic-Responsive, Electrical-Responsive, Ultrasound-Responsive, Enzyme-Responsive, Redox-Responsive, Reactive Oxygen Species (ROS)-Responsive, Glucose-Responsive, Multi-Stimuli-Responsive and Mechanically Responsive), By Material, By Response Mechanism, By Form, By Application, By Deployment Mode, By Country, and By Region Global Industry Analysis, Market Size, Market Share & Forecast from 2026-2033
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Report ID
ANV6261
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Published Date
October 2026
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Pages
294
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Industry
Healthcare
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Base Year
2025
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Historical Data
2019-2024
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Delivery Timeline
24 Hour
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REPORT HIGHLIGHT
Stimuli Responsive Biomaterials Market size was valued at US$ 5,308.1 Million in 2025, expanding at a CAGR of 12.8% from 2026 to 2033.
Stimuli-responsive biomaterials may be defined as biomaterials whose certain physical or chemical properties become modified under the influence of a particular stimulus. The stimulus may be of physical, chemical, or biological nature. Physical stimuli usually include such factors as temperature and pressure changes, while the most common chemical stimuli include changes in pH and ionic strength. Furthermore, there are stimuli-responsive biomaterials that respond to such stimuli as enzymes, magnetic fields, and light. The major features of stimuli-responsive biomaterials can be described as follows: they have the ability to modify their geometry, solubility, or chemical structure via interaction with certain molecules or under certain conditions. These materials are widely used in medicine for drug delivery and tissue engineering because of their ability to interact with the complex environments of living cells and organisms.
Stimuli Responsive Biomaterials Market- Market Dynamics
Growing Adoption of Personalized and Precision Medicine to Drive Market Demand
The growing adoption of personalized and precision medicine is also leading to an increase in the number of stimuli-responsive biomaterials due to their ability to respond to various biological cues, allow for targeted drug delivery, enhance effectiveness, and make treatments tailored to individual patients. In April 2025, according to a study published in the European Union Journal of Public Health, researchers found that there are 20 key areas of improvement for developing personalized medicine through a Europe-China Delphi survey. Ten of the 20 areas are related to research and clinical work, while the other ten areas are related to research funding systems.
The research involved the input of 47 experts, 37 of whom came from the European Union and 10 of whom came from China, in order to develop strategies that can help improve personalized treatment methods. The findings highlighted the importance of phenotyping, standardization of research techniques, application of machine learning algorithms, use of biomarkers, etc.
Stimuli Responsive Biomaterials Market- Segmentation Analysis:
The Global Stimuli Responsive Biomaterials Market is segmented on the basis of Type, Material, Response Mechanism, Form, Application, Deployment Mode, and Region.
From a stimulus type perspective, temperature-responsive biomaterials play a vital role in the Stimuli Responsive Biomaterials Market since the biomaterials change their structure or function based on the change in temperatures, which helps in drug delivery, therapy, and tissue engineering. In September 2025, Lubrizol enhanced its medical materials portfolio in China through the increase in production capacity for medical-grade thermoplastic polyurethane (TPU) and the creation of a Center of Excellence for High-Performance Films dedicated to innovations in medical films. This enhances medical innovations and provides supply capabilities for temperature-sensitive biomaterials.
Based on the application, Tissue Engineering and Regenerative Medicine holds an important position in the Stimuli-Responsive Biomaterials Market, which helps to ensure that the smart biomaterials will be utilized for controlling biological and environmental stimuli and help to achieve cell proliferation, tissue repair, and tissue regeneration to heal the damaged tissues. In June 2026, SkinNexus™ Collag3n, a unique recombinant human identical collagen ingredient developed using artificial intelligence biotechnology, was launched by BASF SE and Bota Biosciences. This highlights the importance of smart biomaterials in the area of regenerative medicine.
Stimuli Responsive Biomaterials Market- Geographical Insights
North America is set to rule the market because of the advanced healthcare infrastructure, research in biomedicine, and large investments in healthcare and biotechnology. For example, by January 2026, according to the report released by the U.S. National Institutes of Health (NIH), NIH-funded research into eye disorders has resulted in saving more than US$28.5 billion in health care costs for Americans. The report states, \"The nationwide research initiatives have established the best single public source of dollars for all types of biomedical and behavioral research. Therefore, North America\'s dominance is maintained by better research funding and infrastructure.
Japan Stimuli Responsive Biomaterials Market - Country Insights
Japan\'s application in the fields of biotechnology, nanotechnology, smart materials, regenerative medicine, tissue engineering, drug markets, and drug delivery systems has helped in making advanced medical devices and advanced medical technologies in Japan. In November 2025, according to the U.S. Department of Commerce, Japan\'s medical device market is estimated to be at US$3,000,000 million and will be worth US$34,240 million in 2025. The report suggests that Japan\'s medical device market is artificial intelligence biotechnology due to Japan\'s aging population and high demand for advanced medical technology. Furthermore, the value of medical device imports into Japan is expected to be US$23,533 million in 2025, which signifies the potential of advanced medical devices in Japan. Therefore, Japan can be considered an attractive market for the advanced medical devices sector.
Stimuli Responsive Biomaterials Market- Competitive Landscape:
The Stimuli-Responsive Biomaterials market is segmented into key players like BASF SE, Evonik Industries AG, Merck KGaA, Solventum Corporation, and Medtronic plc. Every major market player involved in the development of new materials, products, and technologies to meet the growing needs of the healthcare industry. In September 2025, Evonik Industries AG launched clinical-grade VECOLLAN®, which is produced using recombinant non-animal collagen-like protein. The company is optimistic about the potential of the biomaterial because of the possibilities that it offers in the development of medical devices through the production of hydrogels and sponges in the fields of regenerative medicine, orthopedics, and tissue engineering.
Recent Developments:
- In June 2026, Medtronic plc announced the U.S. Food and Drug Administration for its product, the ProGrip™ Advanced self-gripping polypropylene mesh, to be used in robotically assisted ventral hernia repair surgery. The point is made that there are several types of surgical meshes produced by the company.
SCOPE OF THE REPORT
The scope of this report covers the market by its major segments, which include as follows:
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET KEY PLAYERS- DETAILED COMPETITIVE INSIGHTS
- BASF SE
- Evonik Industries AG
- Merck KGaA
- Solventum Corporation
- Medtronic plc
- Lubrizol Corporation
- dsm-firmenich AG
- Corbion N.V.
- CollPlant Biotechnologies Ltd.
- Advanced BioMatrix, Inc.
- GELITA AG
- Anika Therapeutics, Inc.
- Regenity Biosciences
- Integra LifeSciences Holdings Corporation
- Cook Biotech Inc.
- Organogenesis Holdings Inc.
- Others
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY TYPE- MARKET ANALYSIS, 2020 - 2033
- Temperature-Responsive
- pH-Responsive
- Light-Responsive
- Magnetic-Responsive
- Electrical-Responsive
- Ultrasound-Responsive
- Enzyme-Responsive
- Redox-Responsive
- Reactive Oxygen Species (ROS)-Responsive
- Glucose-Responsive
- Multi-Stimuli-Responsive
- Mechanically Responsive
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY MATERIAL- MARKET ANALYSIS, 2020 - 2033
- Hydrogels
- Polymers
- Lipid-Based Materials
- Peptide-Based Materials
- Protein-Based Materials
- Biomimetic Materials
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY RESPONSE MECHANISM- MARKET ANALYSIS, 2020 - 2033
- Swelling and Deswelling
- Phase Transition
- Degradation
- Conformational Change
- Bond Cleavage and Formation
- Self-Assembly and Disassembly
- Sol-Gel Transition
- Permeability Modulation
- Shape-Memory Response
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY FORM- MARKET ANALYSIS, 2020 - 2033
- Nanoparticles
- Microparticles
- Films and Membranes
- Scaffolds
- 3D-Printed Constructs
- Coatings
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY APPLICATION- MARKET ANALYSIS, 2020 - 2033
- Drug Delivery
- Gene Delivery
- Tissue Engineering and Regenerative Medicine
- Wound Healing
- Cancer Therapy
- Cardiovascular
- Orthopedic
- Neurological
- Ophthalmic
- Immunotherapy
- Dental
- Bioimaging
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY DEPLOYMENT MODE- MARKET ANALYSIS, 2020 - 2033
- Injectable
- Implantable
- Topical
- Oral
- Transdermal
- Ocular
- Inhalable
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY REGION- MARKET ANALYSIS, 2020 - 2033
North America
- U.S.
- Canada
Europe
- Germany
- UK
- France
- Italy
- Spain
- The Netherlands
- Sweden
- Russia
- Poland
- Denmark
- Rest of Europe
Asia Pacific
- China
- India
- Japan
- South Korea
- Australia
- Indonesia
- Thailand
- Philippines
- Taiwan
- Vietnam
- Rest of APAC
Latin America
- Brazil
- Mexico
- Argentina
- Colombia
- Rest of LATAM
The Middle East and Africa
- Saudi Arabia
- UAE
- Israel
- Turkey
- Algeria
- Egypt
- Iran
- Qatar
- Rest of MEA
TABLE OF CONTENT
1. Stimuli Responsive Biomaterials Market Overview
1.1. Study Scope
1.2. Market Estimation Years
2. Executive Summary
2.1. Market Snippet
2.2. Competitive Insights
3. Stimuli Responsive Biomaterials Key Market Trends
3.1. Stimuli Responsive Biomaterials Market Drivers
3.1.1. Impact Analysis of Market Drivers
3.2. Stimuli Responsive Biomaterials Market Restraints
3.2.1. Impact Analysis of Market Restraints
3.3. Stimuli Responsive Biomaterials Market Opportunities
3.4. Stimuli Responsive Biomaterials Market Future Trends
4. Stimuli Responsive Biomaterials Industry Study
4.1. PEST Analysis
4.2. Porter’s Five Forces Analysis
4.3. Growth Prospect Mapping
4.4. Regulatory Framework Analysis
5. Stimuli Responsive Biomaterials Market: Impact of Escalating Geopolitical Tensions
5.1. Impact of COVID-19 Pandemic
5.2. Impact of Russia-Ukraine War
5.3. Impact of Middle East Conflicts
6. Stimuli Responsive Biomaterials Market Landscape
6.1. Stimuli Responsive Biomaterials Market Share Analysis, 2025
6.2. Breakdown Data, by Key Manufacturer
6.2.1. Established Players’ Analysis
6.2.2. Emerging Players’ Analysis
7. Stimuli Responsive Biomaterials Market – By Type
7.1. Overview
7.1.1. Segment Share Analysis, By Type, 2025 & 2033 (%)
7.1.2. Temperature-Responsive
7.1.3. pH-Responsive
7.1.4. Light-Responsive
7.1.5. Magnetic-Responsive
7.1.6. Electrical-Responsive
7.1.7. Ultrasound-Responsive
7.1.8. Enzyme-Responsive
7.1.9. Redox-Responsive
7.1.10. Reactive Oxygen Species (ROS)-Responsive
7.1.11. Glucose-Responsive
7.1.12. Multi-Stimuli-Responsive
7.1.13. Mechanically Responsive
8. Stimuli Responsive Biomaterials Market – By Material
8.1. Overview
8.1.1. Segment Share Analysis, By Material, 2025 & 2033 (%)
8.1.2. Hydrogels
8.1.3. Polymers
8.1.4. Lipid-Based Materials
8.1.5. Peptide-Based Materials
8.1.6. Protein-Based Materials
8.1.7. Biomimetic Materials
9. Stimuli Responsive Biomaterials Market – By Response Mechanism
9.1. Overview
9.1.1. Segment Share Analysis, By Response Mechanism, 2025 & 2033 (%)
9.1.2. Swelling and Deswelling
9.1.3. Phase Transition
9.1.4. Degradation
9.1.5. Conformational Change
9.1.6. Bond Cleavage and Formation
9.1.7. Self-Assembly and Disassembly
9.1.8. Sol-Gel Transition
9.1.9. Permeability Modulation
9.1.10. Shape-Memory Response
10. Stimuli Responsive Biomaterials Market – By Form
10.1. Overview
10.1.1. Segment Share Analysis, By Form, 2025 & 2033 (%)
10.1.2. Nanoparticles
10.1.3. Microparticles
10.1.4. Films and Membranes
10.1.5. Scaffolds
10.1.6. 3D-Printed Constructs
10.1.7. Coatings
11. Stimuli Responsive Biomaterials Market – By Application
11.1. Overview
11.1.1. Segment Share Analysis, By Application, 2025 & 2033 (%)
11.1.2. Drug Delivery
11.1.3. Gene Delivery
11.1.4. Tissue Engineering and Regenerative Medicine
11.1.5. Wound Healing
11.1.6. Cancer Therapy
11.1.7. Cardiovascular
11.1.8. Orthopedic
11.1.9. Neurological
11.1.10. Ophthalmic
11.1.11. Immunotherapy
11.1.12. Dental
11.1.13. Bioimaging
12. Stimuli Responsive Biomaterials Market – By Deployment Mode
12.1. Overview
12.1.1. Segment Share Analysis, By Deployment Mode, 2025 & 2033 (%)
12.1.2. Injectable
12.1.3. Implantable
12.1.4. Topical
12.1.5. Oral
12.1.6. Transdermal
12.1.7. Ocular
12.1.8. Inhalable
13. Stimuli Responsive Biomaterials Market – By Geography
13.1. Introduction
13.1.1. Segment Share Analysis, By Geography, 2025 & 2033 (%)
13.2. North America
13.2.1. Overview
13.2.2. Stimuli Responsive Biomaterials Key Manufacturers in North America
13.2.3. North America Market Size and Forecast, By Country, 2020 - 2033 (US$ Million)
13.2.4. North America Market Size and Forecast, By Type, 2020 - 2033 (US$ Million)
13.2.5. North America Market Size and Forecast, By Material, 2020 - 2033 (US$ Million)
13.2.6. North America Market Size and Forecast, By Response Mechanism, 2020 - 2033 (US$ Million)
13.2.7. North America Market Size and Forecast, By Form, 2020 - 2033 (US$ Million)
13.2.8. North America Market Size and Forecast, By Application, 2020 - 2033 (US$ Million)
13.2.9. North America Market Size and Forecast, By Deployment Mode, 2020 - 2033 (US$ Million)
13.2.10. U.S.
13.2.11. Canada
13.3. Europe
13.3.1. Overview
13.3.2. Stimuli Responsive Biomaterials Key Manufacturers in Europe
13.3.3. Europe Market Size and Forecast, By Country, 2020 - 2033 (US$ Million)
13.3.4. Europe Market Size and Forecast, By Type, 2020 - 2033 (US$ Million)
13.3.5. Europe Market Size and Forecast, By Material, 2020 - 2033 (US$ Million)
13.3.6. Europe Market Size and Forecast, By Response Mechanism, 2020 - 2033 (US$ Million)
13.3.7. Europe Market Size and Forecast, By Form, 2020 - 2033 (US$ Million)
13.3.8. Europe Market Size and Forecast, By Application, 2020 - 2033 (US$ Million)
13.3.9. Europe Market Size and Forecast, By Deployment Mode, 2020 - 2033 (US$ Million)
13.3.10. Germany
13.3.11. UK
13.3.12. France
13.3.13. Italy
13.3.14. Spain
13.3.15. The Netherlands
13.3.16. Sweden
13.3.17. Russia
13.3.18. Poland
13.3.19. Denmark
13.3.20. Rest of Europe
13.4. Asia Pacific (APAC)
13.4.1. Overview
13.4.2. Stimuli Responsive Biomaterials Key Manufacturers in Asia Pacific
13.4.3. APAC Market Size and Forecast, By Country, 2020 - 2033 (US$ Million)
13.4.4. APAC Market Size and Forecast, By Type, 2020 - 2033 (US$ Million)
13.4.5. APAC Market Size and Forecast, By Material, 2020 - 2033 (US$ Million)
13.4.6. APAC Market Size and Forecast, By Response Mechanism, 2020 - 2033 (US$ Million)
13.4.7. APAC Market Size and Forecast, By Form, 2020 - 2033 (US$ Million)
13.4.8. APAC Market Size and Forecast, By Application, 2020 - 2033 (US$ Million)
13.4.9. APAC Market Size and Forecast, By Deployment Mode, 2020 - 2033 (US$ Million)
13.4.10. China
13.4.11. India
13.4.12. Japan
13.4.13. South Korea
13.4.14. Australia
13.4.15. Indonesia
13.4.16. Thailand
13.4.17. Philippines
13.4.18. Taiwan
13.4.19. Vietnam
13.4.20. Rest of APAC
13.5. Latin America (LATAM)
13.5.1. Overview
13.5.2. Stimuli Responsive Biomaterials Key Manufacturers in Latin America
13.5.3. LATAM Market Size and Forecast, By Country, 2020 - 2033 (US$ Million)
13.5.4. LATAM Market Size and Forecast, By Type, 2020 - 2033 (US$ Million)
13.5.5. LATAM Market Size and Forecast, By Material, 2020 - 2033 (US$ Million)
13.5.6. LATAM Market Size and Forecast, By Response Mechanism, 2020 - 2033 (US$ Million)
13.5.7. LATAM Market Size and Forecast, By Form, 2020 - 2033 (US$ Million)
13.5.8. LATAMSize and Forecast, By Application, 2020 - 2033 (US$ Million)
13.5.9. LATAM Size and Forecast, By Deployment Mode, 2020 - 2033 (US$ Million)
13.5.10. Brazil
13.5.11. Mexico
13.5.12. Argentina
13.5.13. Colombia
13.5.14. Rest of LATAM
13.6. Middle East and Africa
13.6.1. Overview
13.6.2. Stimuli Responsive Biomaterials Key Manufacturers in Middle East and Africa
13.6.3. Middle East and Africa Market Size and Forecast, By Country, 2020 - 2033 (US$ Million)
13.6.4. Middle East and Africa Market Size and Forecast, By Type, 2020 - 2033 (US$ Million)
13.6.5. Middle East and Africa Market Size and Forecast, By Material, 2020 - 2033 (US$ Million)
13.6.6. Middle East and Africa Market Size and Forecast, By Response Mechanism, 2020 - 2033 (US$ Million)
13.6.7. Middle East and Africa Market Size and Forecast, By Form, 2020 - 2033 (US$ Million)
13.6.8. Middle East and Africa Market Size and Forecast, By Application, 2020 - 2033 (US$ Million)
13.6.9. Middle East and Africa Market Size and Forecast, By Deployment Mode, 2020 - 2033 (US$ Million)
13.6.10. Saudi Arabia
13.6.11. UAE
13.6.12. Israel
13.6.13. Turkey
13.6.14. Algeria
13.6.15. Egypt
13.6.16. Iran
13.6.17. Qatar
13.6.18. Rest of MEA
14. Key Vendor Analysis- Stimuli Responsive Biomaterials Industry
14.1. Competitive Benchmarking
14.1.1. Competitive Dashboard
14.1.2. Competitive Positioning
14.2. Company Profiles
14.2.1. BASF SE
14.2.2. Evonik Industries AG
14.2.3. Merck KGaA
14.2.4. Solventum Corporation
14.2.5. Medtronic plc
14.2.6. Lubrizol Corporation
14.2.7. dsm-firmenich AG
14.2.8. Corbion N.V.
14.2.9. CollPlant Biotechnologies Ltd.
14.2.10. Advanced BioMatrix, Inc.
14.2.11. GELITA AG
14.2.12. Anika Therapeutics, Inc.
14.2.13. Regenity Biosciences
14.2.14. Integra LifeSciences Holdings Corporation
14.2.15. Cook Biotech Inc.
14.2.16. Organogenesis Holdings Inc.
14.2.17. Others
15. 360 Degree AnalystView
16. Appendix
16.1. Research Methodology
16.2. References
16.3. Abbreviations
16.4. Disclaimer
16.5. Contact Us
SCOPE OF THE REPORT
The scope of this report covers the market by its major segments, which include as follows:
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET KEY PLAYERS- DETAILED COMPETITIVE INSIGHTS
- BASF SE
- Evonik Industries AG
- Merck KGaA
- Solventum Corporation
- Medtronic plc
- Lubrizol Corporation
- dsm-firmenich AG
- Corbion N.V.
- CollPlant Biotechnologies Ltd.
- Advanced BioMatrix, Inc.
- GELITA AG
- Anika Therapeutics, Inc.
- Regenity Biosciences
- Integra LifeSciences Holdings Corporation
- Cook Biotech Inc.
- Organogenesis Holdings Inc.
- Others
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY TYPE- MARKET ANALYSIS, 2020 - 2033
- Temperature-Responsive
- pH-Responsive
- Light-Responsive
- Magnetic-Responsive
- Electrical-Responsive
- Ultrasound-Responsive
- Enzyme-Responsive
- Redox-Responsive
- Reactive Oxygen Species (ROS)-Responsive
- Glucose-Responsive
- Multi-Stimuli-Responsive
- Mechanically Responsive
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY MATERIAL- MARKET ANALYSIS, 2020 - 2033
- Hydrogels
- Polymers
- Lipid-Based Materials
- Peptide-Based Materials
- Protein-Based Materials
- Biomimetic Materials
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY RESPONSE MECHANISM- MARKET ANALYSIS, 2020 - 2033
- Swelling and Deswelling
- Phase Transition
- Degradation
- Conformational Change
- Bond Cleavage and Formation
- Self-Assembly and Disassembly
- Sol-Gel Transition
- Permeability Modulation
- Shape-Memory Response
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY FORM- MARKET ANALYSIS, 2020 - 2033
- Nanoparticles
- Microparticles
- Films and Membranes
- Scaffolds
- 3D-Printed Constructs
- Coatings
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY APPLICATION- MARKET ANALYSIS, 2020 - 2033
- Drug Delivery
- Gene Delivery
- Tissue Engineering and Regenerative Medicine
- Wound Healing
- Cancer Therapy
- Cardiovascular
- Orthopedic
- Neurological
- Ophthalmic
- Immunotherapy
- Dental
- Bioimaging
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY DEPLOYMENT MODE- MARKET ANALYSIS, 2020 - 2033
- Injectable
- Implantable
- Topical
- Oral
- Transdermal
- Ocular
- Inhalable
GLOBAL STIMULI RESPONSIVE BIOMATERIALS MARKET, BY REGION- MARKET ANALYSIS, 2020 - 2033
North America
- U.S.
- Canada
Europe
- Germany
- UK
- France
- Italy
- Spain
- The Netherlands
- Sweden
- Russia
- Poland
- Denmark
- Rest of Europe
Asia Pacific
- China
- India
- Japan
- South Korea
- Australia
- Indonesia
- Thailand
- Philippines
- Taiwan
- Vietnam
- Rest of APAC
Latin America
- Brazil
- Mexico
- Argentina
- Colombia
- Rest of LATAM
The Middle East and Africa
- Saudi Arabia
- UAE
- Israel
- Turkey
- Algeria
- Egypt
- Iran
- Qatar
- Rest of MEA
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